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KMID : 0895820020120040001
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Journal of Oriental Rehabilitation Medicine
2002 Volume.12 No. 4 p.1 ~ p.0
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The Effects of Sochungryongtang on Obesity and Antioxidanta ctivities in Zucker rat
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Kim Bong-Chan
Lee Myeong-Jong
Keum Dong-Ho
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Abstract
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Objective: This study was carried out to examine the effect of Sochungryongtang(ST) on obesity and antioxidation.
Methods and Materials: ST was investigated effects of obesity and antioxidation for DPPH radical ability, nitrate reductase activity, total body weight and fed ratio, serum glucose content, serum triglyceride and total cholesterol content, serum GPT and GOT content, serum leptin content, catalase activity, superoxide dismutase activity, lipidperoxidation and glutathione activity. In this experiment rats were divided into 4 group, Lean control; non-treated, Lean B; ST, Fat control; non treated, Fat B; ST, Each value is the mean ± S.E for 3 separate experiments.
Conclusions: In vitro, DPPH radical ability and nitrate reductase activity were increased according to the increasing of ST concentrations. In vivo, compared with Fat control group, the serum glucose content, the serum triglyceride content, the serum total cholesterol content the serum GPT and the serum GOT content were decreased in Fat B group. The serum leptin content was not increased significantly. Catalase activity, superoxide dismutase activity, and glutathione activity were increased and lipidperoxidation was decreased in Fat B group compared with Fat control group. According to the above results, the obesity and the antioxidant activities of ST were proved in experiment and it should be studied and developed more throughly.
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KEYWORD
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Sochungryongtang, obesity, antioxidant activity
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